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Hyperinsulinemic hypoglycemia describes the condition and effects of low blood glucose caused by excessive insulin. Hypoglycemia due to excess insulin is the most common type of serious hypoglycemia. It can be due to endogenous or injected insulin. ==Causes== Hypoglycemia due to endogenous insulin can be congenital or acquired, apparent in the newborn period, or many years later. The hypoglycemia can be severe and life-threatening or a minor, occasional nuisance. By far the most common type of severe but transient hyperinsulinemic hypoglycemia occurs accidentally in persons with type 1 diabetes who take insulin. *Hypoglycemia due to endogenous insulin * *Congenital hyperinsulinism * * *Transient neonatal hyperinsulinism (mechanism not known) * * *Focal hyperinsulinism (KATP channel disorders) * * * *Paternal SUR1 mutation with clonal loss of heterozygosity of 11p15 * * * *Paternal Kir6.2 mutation with clonal loss of heterozygosity of 11p15 * * *Diffuse hyperinsulinism * * * *KATP channel disorders * * * * *SUR1 mutations * * * * *Kir6.2 mutations * * * *Glucokinase gain-of-function mutations * * * *Hyperammonemic hyperinsulinism (glutamate dehydrogenase gain-of-function mutations) * * * *Short chain acyl coenzyme A dehydrogenase deficiency * * * *Carbohydrate-deficient glycoprotein syndrome (Jaeken's Disease) * * * *Beckwith-Wiedemann syndrome(suspected due to hyperinsulinism but pathophysiology uncertain: 11p15 mutation or IGF2 excess) * *Acquired forms of hyperinsulinism * *Insulinomas (insulin-secreting tumors) * * *Islet cell adenoma or adenomatosis * * *Islet cell carcinoma * *Adult nesidioblastosis * *Autoimmune insulin syndrome * *Noninsulinoma pancreatogenous hypoglycemia * *Reactive hypoglycemia (also see idiopathic postprandial syndrome) * *Gastric dumping syndrome *Drug induced hyperinsulinism * *Sulfonylurea * *Aspirin * *Pentamidine * *Quinine * *Disopyramide * *Bordetella pertussis vaccine or infection * *D-chiro-inositol and myo-inositol *Hypoglycemia due to exogenous (injected) insulin * *Insulin self-injected for treatment of diabetes (i.e., diabetic hypoglycemia) * *Insulin self-injected surreptitiously (e.g., Munchausen syndrome) * *Insulin self-injected in a suicide attempt or successful suicide * *Various forms of diagnostic challenge or "tolerance tests" * * *Insulin tolerance test for pituitary or adrenergic response assessment * * *Protein challenge * * *Leucine challenge * * *Tolbutamide challenge * *Insulin potentiation therapy * *Insulin-induced coma for depression treatment 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hyperinsulinemic hypoglycemia」の詳細全文を読む スポンサード リンク
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